Konstantin Shevchenko-Bitenskyi, Valeriy Bitenskyi. Innovative Direction in Theatment of Mental Illness Using Synergetic Effects of Brain Tissues.

(2020) Science and education, 2, 57-64. Odessa.

Konstantin Shevchenko-Bitenskyi,
PhD (Candidate of Medical Sciences),
State institution “South Ukrainian National Pedagogical University named after K. D. Ushynsky”,
26, Staroportofrankovskaya Str., Odessa, Ukraine
Valeriy Bitenskyi,
Doctor of Medical Sciences, professor,
corresponding member of the National Academy of Medical Sciences of Ukraine,
State institution “South Ukrainian National Pedagogical University named after K. D. Ushynsky”,
26, Staroportofrankovskaya Str., Odessa, Ukraine


INNOVATIVE DIRECTION IN THEATMENT OF MENTAL ILLNESS USING SYNERGETIC
EFFECTS OF BRAIN TISSUES


SUMMARY:

All etiopathogenetic concepts in modern medicine are based on causal, linear and deterministic relationships. The diseases with an unknown etiology obviously do not have pathogenesis and in relation to that there is no adequate therapy to date. Psychopharmacologists create pharma drugs for the treatment of mental illness based on the same linear principles. However, since the 60s of the 20th century, thanks to the discoveries of many great scientists (for example, Ilya Prigozhin –Nobel Laureate), ideas about nonlinear systems in the nature of the Earth and Human began to develop (Haken, 2007). In particular, most of the serious mental illnesses are classified as open, non-linear, unstable, selforganizing systems. It is obviously that these systems should be changed under the influence of “throwing” into their chaotic structure of a disturbing agent, creating new systems instead of painful ones on the basis of adaptive effects of pre- and postconditioning (PreC; PostC). We have examined and carried out a therapy with a “non-linear” complex of effects of cerebral hypo- and hyperthermia, inhalation of xenon (Xe) and nitrous oxide (N₂O) using intravenous induction and inhalation of valproate (normotimic effect) in 85 patients with obsessive-compulsive disorders. A statistically significant (p> 0.001) therapeutic effect has been obtained in almost 100% (92%) of patients.


KEYWORDS:

Synergetics, non-linear self-organizing open system, dissipative structure, fractals, preconditioning, chaos, obsessive-compulsive disorder.


FULL TEXT:

 


REFERENCES:

1. Aboloni, A. F., Bohan, N. A., Mendel, A. I. (2007). Toposelektivnoe EEG-kartirovanie golovnogo mozha u bolnykh alkogolizmom s komorbidnymi organicheskim porazheniem golovnogo mozga [Toposelective EEG mapping of the brain in patients with alcoholism with comorbid organic brain damage]. Proceedings from  All-Russian scientific-practical conference “Kolichestvennaja JeJeG i nejroterapija” – “Quantitative EEG and neurotherapy”, (pp. 167-171). St. Petersburg [in Russian].
2. Avedisova, A. S. (2017). Terapiya rasstroystv sna: sovremennye podhody k naznacheniyu gipnotikov [Therapy of sleep disorders: modern approaches to the appointment of hypnotics]. Moscow: MIA [in Russian].
3. Aleksandrovsky, Yu. A. (2000). Pogranichnye psihicheskie rasstrojstva [Borderline Mental Disorders]. Moscow: Medicine [in Russian].
4. Bitensky, V. S., Lobasyuk, B. A., Bodelan, M. I. (2010). Neyropsikhologiya i neyropsikhiatriya (issledovaniya parallelizma psikhicheskikh fenomenov i elektrofiziolhii mozga) [Neuropsychology and neuropsychiatry (studies of the parallelism of mental phenomena and brain electrophysiology)]. Vіsnik psikkhіatrіi ta psikhofarmakoterapіi – Bulletin of Psychiatry and Psychopharmacotherapy, 2 (18), 26–32 [in Russian].
5. Bitensky, V. S. (2010). Zvyazok mіzh haosom, noogennim prostorom і kіndlіngovim mehanіzmom psikhіchnikh rozladіv [The relationship between chaos, nogenous space and the Kindling mechanism of mental disorders]. Proceedings from International student scientific conference. (pp. 138–141). Odessa [in Russian].
6. Ershova-Babenko, I. V. (1993). Metodologiya issledovaniya psikhiki kak sinergeticheskogo obiekta [The methodology of the study of the psyche as a synergistic object]. Odessa: ODECOM [in Russian].
7. Ershova-Babenko, I. V. (2007). Sbornik lektsiy po psikhosinergetike [A collection of lectures on psychosynergetics]. Odessa [in Russian].
8. Ershova-Babenko, I. V. (2015). Psychosynergetics [Psihosinergetika]. Kherson. 2015 [in Russian].
9. Ershova-Babenko, I. V. (2005). Psikhosinergeticheskie strategii chelovecheskoy deyatelnosti (Kontseptualnaya model) [Psychosynergetic strategies of human activity (Conceptual model)]. Vinnitsa [in Russian].
10. Kropotov, D. Yu. (2010). Kolichestvennaya EEG, kognitivnye vyzvannye potentsialy mozga cheloveka i neyroterapii [Quantitative EEG, cognitive evoked potentials of the human brain and neurotherapy]. Donetsk [in Russian].
11. Mosolov, S. N. (2018). Dostizheniya, problemy i perspektivy farmakoterapii psikhicheskikh rasstroystv [Achievements, problems and prospects of pharmacotherapy of mental disorders]. Proceedings from the scientificpractical conference “Interdisciplinary approaches to the study of mental health of a person and society”. (pp. 21- 31). Moscow, October 29, 2018. Moscow [in Russian].
12. Prigogine, I. (1985). Ot sushhestvuyushchikh k voznikayushhemu. Vremya i slozhnost v fizicheskikh naukakh [From existing to emerging. Time and complexity in the physical sciences]. Moscow [in Russian].
13. Slezin, V. B., Korsakov, E. A., & Schulz, E. V. (2007). Fraktalnyy analiz EEG v izuchenii fiziolog icheskikh mekhanizmov paranoidnoy, shizoaffektivnoy i shizotipicheskoy shizofrenii [Fractal analysis of EEG in the study of physiological mechanisms of paranoid, schizoaffective and schizotypic schizophrenia]. Proceedings from the All-Russian scientific-practical conference "Quantitative EEG and neurotherapy". (pp. 132–137). St. Petersburg [in Russian].
14. Smulevich, A. B. (2001). Depressii v obshchey medicine [Depression in general medicine]. Moscow: Medical News Agency [in Russian].
15. Haken, H. (2007). Printsipy raboty golovnogo mozga. Sinergeticheskiy podhod k aktivnosti mozga, povedeniyu i kognitivnoy deyatelnosti [Principles of the brain. A synergistic approach to brain activity, behavior and cognitive activity]. Moscow [in Russian].
16. Chernobrovkina, T. V., & Kershengolts, B. M. (2013). Problemy soznaniya vzavisimostyakh. Sinergeticheskiy podkhod [The problems of consciousness in dependencies. Synergetic approach]. (pp. 462-538). Kharkov [in Russian].
17. Goldberg, A. I. (1996). Non-lineral dynamics for clinicians. Lancet, 374, 1312–1314 [in English].
18. Haken, H. (1980). Synergetic. Мoscow: Mir [in English].
19. Jung, J. G. (1954). The development of personality. London; Routledge [in English].
20. Lorenz, E. N. (1986). Large-scrate monions of the atmosphere. In Advance in Earth/Science. (pp. 95– 109). Cambridge; M. A.: MJT Press [in English].
21. Mackay, M., & Glass, I. (1977) Oscillation and chaos in physiological control system. Science [in English].
22. Mandell, A. J. (1985). From molecular biological simplification to more realistic central nervous system dynamics: an opinion. In Psychobiological Foundation of clinical Psychiatry. O. Cavenar (Eds.), pp. 361–366. New York: Lippincott [in English].
23. Murry, C. E., Jennings, R. B., & Reimer, K. A. (1986). Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. Vol. 74, № 5. P. 1124–1136 [in English].
24. Paulus, M. P., Geyer, M. A., & Braff, D. L. (1996). Use of methods from chaos theory to quantify a fundamental dysfunction I the behavioral organization of schizophrenic patients. American Journal of Psychiatry, 153, 714- 717 [in English].
25. Poitingen, H., & Richter, P. (1986). The Beauty of Fractals. Berlin: Spingel-Verlad [in English].
26. Reid, Steven. (1998). Butterflies, fractal and psychiatry. Psychiatric Bulletin, 22, 568–570 [in English].

         

       
   
   
         

 

©2024 Університет Ушинського. Всі права захищені, мабуть.